E67D (p.Glu67Asp) variant of FTO (Q9C0B1)
E67D (p.Glu67Asp) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
E67D (p.Glu67Asp) variant details
- p.Glu67Asp
- TOPMed rs975320571
- gnomAD rs975320571
- Missense
- Variant Prioritization Score for Impact Estimate 0.0988
- REVEL 0.07
- CADD 9.76
- PolyPhen-2 0.08
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available