E64G (p.Glu64Gly) variant of FTO (Q9C0B1)
E64G (p.Glu64Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E64G (p.Glu64Gly) variant details
- p.Glu64Gly
- ExAC rs778727414
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.24
- CADD 23.80
- PolyPhen-2 0.90
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available