E11Q (p.Glu11Gln) variant of FTO (Q9C0B1)
E11Q (p.Glu11Gln) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
E11Q (p.Glu11Gln) variant details
- p.Glu11Gln
- gnomAD 16-53704215-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.21
- CADD 26.10
- PolyPhen-2 0.99
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available