E11G (p.Glu11Gly) variant of FTO (Q9C0B1)
E11G (p.Glu11Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
E11G (p.Glu11Gly) variant details
- p.Glu11Gly
- gnomAD 16-53704216-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.26
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available