E11D (p.Glu11Asp) variant of FTO (Q9C0B1)
E11D (p.Glu11Asp) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
E11D (p.Glu11Asp) variant details
- p.Glu11Asp
- TOPMed rs1388384491
- gnomAD rs1388384491
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.20
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available