D36N (p.Asp36Asn) variant of FTO (Q9C0B1)
D36N (p.Asp36Asn) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
D36N (p.Asp36Asn) variant details
- p.Asp36Asn
- gnomAD 16-53810200-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.33
- MetaLR 0.41
- MetaSVM -0.17
- CADD 25.20
- PolyPhen-2 0.67
- SIFT 0.48
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available