D36G (p.Asp36Gly) variant of FTO (Q9C0B1)
D36G (p.Asp36Gly) in FTO (Q9C0B1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
D36G (p.Asp36Gly) variant details
- p.Asp36Gly
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.41
- CADD 22.80
- PolyPhen-2 0.33
- SIFT 0.26
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available