D35N (p.Asp35Asn) variant of FTO (Q9C0B1)
D35N (p.Asp35Asn) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
D35N (p.Asp35Asn) variant details
- p.Asp35Asn
- TOPMed rs2078484206
- Missense
- Variant Prioritization Score for Impact Estimate 0.642
- REVEL 0.60
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available