D25V (p.Asp25Val) variant of FTO (Q9C0B1)
D25V (p.Asp25Val) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
D25V (p.Asp25Val) variant details
- p.Asp25Val
- gnomAD 16-53810168-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.5
- REVEL 0.46
- MetaLR 0.29
- MetaSVM -0.44
- CADD 26.10
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available