D25E (p.Asp25Glu) variant of FTO (Q9C0B1)
D25E (p.Asp25Glu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
D25E (p.Asp25Glu) variant details
- p.Asp25Glu
- gnomAD 16-53810169-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.19
- MetaLR 0.10
- MetaSVM -1.03
- CADD 17.10
- PolyPhen-2 0.45
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available