A68S (p.Ala68Ser) variant of FTO (Q9C0B1)
A68S (p.Ala68Ser) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
A68S (p.Ala68Ser) variant details
- p.Ala68Ser
- gnomAD 16-53825942-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.586
- REVEL 0.53
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available