A68D (p.Ala68Asp) variant of FTO (Q9C0B1)
A68D (p.Ala68Asp) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
A68D (p.Ala68Asp) variant details
- p.Ala68Asp
- gnomAD 16-53825943-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.817
- REVEL 0.85
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available