A14G (p.Ala14Gly) variant of FTO (Q9C0B1)
A14G (p.Ala14Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
A14G (p.Ala14Gly) variant details
- p.Ala14Gly
- TOPMed rs1768475718
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- REVEL 0.23
- CADD 32.00
- PolyPhen-2 0.88
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available