S35N (p.Ser35Asn) variant of FSHR (P23945)
S35N (p.Ser35Asn) in FSHR (P23945) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
S35N (p.Ser35Asn) variant details
- p.Ser35Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.563
- REVEL 0.46
- MetaLR 0.92
- MetaSVM 0.99
- CADD 19.80
- PolyPhen-2 0.03
- SIFT 0.29
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available