L83F (p.Leu83Phe) variant of FSHR (P23945)
L83F (p.Leu83Phe) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
L83F (p.Leu83Phe) variant details
- p.Leu83Phe
- Ensembl rs1667637107
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.56
- MetaLR 0.65
- MetaSVM 0.16
- CADD 24.20
- PolyPhen-2 0.72
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available