L51M (p.Leu51Met) variant of FSHR (P23945)
L51M (p.Leu51Met) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L51M (p.Leu51Met) variant details
- p.Leu51Met
- ExAC rs764329561
- gnomAD rs764329561
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.60
- MetaLR 0.78
- MetaSVM 0.58
- CADD 26.20
- PolyPhen-2 0.49
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available