K74N (p.Lys74Asn) variant of FSHR (P23945)
K74N (p.Lys74Asn) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K74N (p.Lys74Asn) variant details
- p.Lys74Asn
- gnomAD rs1004632178
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.25
- MetaLR 0.46
- MetaSVM -0.17
- CADD 24.60
- PolyPhen-2 0.02
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available