I61T (p.Ile61Thr) variant of FSHR (P23945)
I61T (p.Ile61Thr) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
I61T (p.Ile61Thr) variant details
- p.Ile61Thr
- ExAC rs772911094
- TOPMed rs772911094
- gnomAD rs772911094
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.86
- MetaLR 0.78
- MetaSVM 0.68
- CADD 26.50
- PolyPhen-2 0.80
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available