I22V (p.Ile22Val) variant of FSHR (P23945)
I22V (p.Ile22Val) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I22V (p.Ile22Val) variant details
- p.Ile22Val
- gnomAD rs1673169581
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.28
- MetaLR 0.74
- MetaSVM -0.16
- CADD 9.99
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available