F66I (p.Phe66Ile) variant of FSHR (P23945)
F66I (p.Phe66Ile) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
F66I (p.Phe66Ile) variant details
- p.Phe66Ile
- gnomAD rs749701827
- Missense
- Variant Prioritization Score for Impact Estimate 0.797
- REVEL 0.88
- MetaLR 0.84
- MetaSVM 0.83
- CADD 26.50
- PolyPhen-2 0.95
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available