E87D (p.Glu87Asp) variant of FSHR (P23945)
E87D (p.Glu87Asp) in FSHR (P23945) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
E87D (p.Glu87Asp) variant details
- p.Glu87Asp
- TOPMed rs267599405
- gnomAD rs267599405
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- REVEL 0.49
- MetaLR 0.55
- MetaSVM -0.19
- CADD 23.30
- PolyPhen-2 0.53
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available