T7I (p.Thr7Ile) variant of FOXP2 (Forkhead box protein P2)
T7I (p.Thr7Ile) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T7I (p.Thr7Ile) variant details
- p.Thr7Ile
- ESP rs377372067
- ExAC rs377372067
- TOPMed rs377372067
- gnomAD rs377372067
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.22
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available