T40I (p.Thr40Ile) variant of FOXP2 (Forkhead box protein P2)
T40I (p.Thr40Ile) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T40I (p.Thr40Ile) variant details
- p.Thr40Ile
- 1000Genomes rs185960561
- TOPMed rs185960561
- gnomAD rs185960561
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.24
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available