T22S (p.Thr22Ser) variant of FOXP2 (Forkhead box protein P2)
T22S (p.Thr22Ser) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
T22S (p.Thr22Ser) variant details
- p.Thr22Ser
- gnomAD 7-114426575-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.09
- MetaLR 0.45
- MetaSVM -0.31
- CADD 17.90
- PolyPhen-2 0.11
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available