S5Y (p.Ser5Tyr) variant of FOXP2 (Forkhead box protein P2)
S5Y (p.Ser5Tyr) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
S5Y (p.Ser5Tyr) variant details
- p.Ser5Tyr
- gnomAD rs1793858227
- Missense
- Variant Prioritization Score for Impact Estimate 0.719
- REVEL 0.68
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available