S45T (p.Ser45Thr) variant of FOXP2 (Forkhead box protein P2)
S45T (p.Ser45Thr) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S45T (p.Ser45Thr) variant details
- p.Ser45Thr
- ESP rs377588856
- ExAC rs377588856
- TOPMed rs377588856
- gnomAD rs377588856
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- REVEL 0.27
- CADD 23.80
- PolyPhen-2 0.47
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available