S41T (p.Ser41Thr) variant of FOXP2 (Forkhead box protein P2)
S41T (p.Ser41Thr) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
S41T (p.Ser41Thr) variant details
- p.Ser41Thr
- gnomAD 7-114426633-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.14
- MetaLR 0.68
- MetaSVM 0.53
- CADD 23.80
- PolyPhen-2 0.78
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available