S14L (p.Ser14Leu) variant of FOXP2 (Forkhead box protein P2)
S14L (p.Ser14Leu) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
S14L (p.Ser14Leu) variant details
- p.Ser14Leu
- gnomAD 7-114426552-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- REVEL 0.28
- MetaLR 0.78
- MetaSVM 0.74
- CADD 26.40
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available