R62G (p.Arg62Gly) variant of FOXP2 (Forkhead box protein P2)
R62G (p.Arg62Gly) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
R62G (p.Arg62Gly) variant details
- p.Arg62Gly
- gnomAD 7-114534632-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.34
- MetaLR 0.89
- MetaSVM 0.96
- CADD 27.20
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available