Q17R (p.Gln17Arg) variant of FOXP2 (Forkhead box protein P2)
Q17R (p.Gln17Arg) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
Q17R (p.Gln17Arg) variant details
- p.Gln17Arg
- gnomAD 7-114426561-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.25
- MetaLR 0.86
- MetaSVM 0.92
- CADD 25.40
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available