M20I (p.Met20Ile) variant of FOXP2 (Forkhead box protein P2)
M20I (p.Met20Ile) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
M20I (p.Met20Ile) variant details
- p.Met20Ile
- gnomAD 7-114426571-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.21
- MetaLR 0.66
- MetaSVM 0.30
- CADD 23.60
- PolyPhen-2 0.28
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available