L65V (p.Leu65Val) variant of FOXP2 (Forkhead box protein P2)
L65V (p.Leu65Val) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L65V (p.Leu65Val) variant details
- p.Leu65Val
- gnomAD 7-114534641-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.10
- MetaLR 0.84
- MetaSVM 0.76
- CADD 23.70
- PolyPhen-2 0.93
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available