L23R (p.Leu23Arg) variant of FOXP2 (Forkhead box protein P2)
L23R (p.Leu23Arg) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L23R (p.Leu23Arg) variant details
- p.Leu23Arg
- ExAC rs745618497
- gnomAD rs745618497
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.29
- CADD 26.40
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available