I10V (p.Ile10Val) variant of FOXP2 (Forkhead box protein P2)
I10V (p.Ile10Val) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
I10V (p.Ile10Val) variant details
- p.Ile10Val
- gnomAD 7-114426539-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.475
- REVEL 0.26
- MetaLR 0.80
- MetaSVM 0.76
- CADD 24.50
- PolyPhen-2 0.66
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available