A60G (p.Ala60Gly) variant of FOXP2 (Forkhead box protein P2)
A60G (p.Ala60Gly) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
A60G (p.Ala60Gly) variant details
- p.Ala60Gly
- gnomAD 7-114534627-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.23
- MetaLR 0.77
- MetaSVM 0.72
- CADD 24.90
- PolyPhen-2 0.92
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available