A57T (p.Ala57Thr) variant of FOXP2 (Forkhead box protein P2)
A57T (p.Ala57Thr) in FOXP2 (Forkhead box protein P2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
A57T (p.Ala57Thr) variant details
- p.Ala57Thr
- ExAC rs748073993
- TOPMed rs748073993
- gnomAD rs748073993
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.26
- CADD 32.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available