T41R (p.Thr41Arg) variant of FOXP1 (Forkhead box protein P1)
T41R (p.Thr41Arg) in FOXP1 (Forkhead box protein P1) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
T41R (p.Thr41Arg) variant details
- p.Thr41Arg
- ExAC rs756099573
- TOPMed rs756099573
- gnomAD rs756099573
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- CADD 27.00
- PolyPhen-2 0.33
- SIFT 0.02
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available