R36W (p.Arg36Trp) variant of FOXP1 (Forkhead box protein P1)
R36W (p.Arg36Trp) in FOXP1 (Forkhead box protein P1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R36W (p.Arg36Trp) variant details
- p.Arg36Trp
- rs935869094
- NCI-TCGA Cosmic COSV5951
- cosmic curated COSV59516
- TOPMed rs935869094
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- CADD 28.20
- PolyPhen-2 0.97
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available