K10R (p.Lys10Arg) variant of FOXP1 (Forkhead box protein P1)
K10R (p.Lys10Arg) in FOXP1 (Forkhead box protein P1) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K10R (p.Lys10Arg) variant details
- p.Lys10Arg
- rs1476826805
- ClinGen CA353565277
- ClinVar RCV002623149
- gnomAD rs1476826805
- Likely benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- CADD 23.70
- PolyPhen-2 0.00
- SIFT 0.02
- ClinVar: Likely benign (not provided)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available