V7M (p.Val7Met) variant of FOXO1 (Forkhead box protein O1)
V7M (p.Val7Met) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
V7M (p.Val7Met) variant details
- p.Val7Met
- TOPMed rs933517374
- gnomAD rs933517374
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.21
- MetaLR 0.62
- MetaSVM -0.13
- CADD 18.80
- PolyPhen-2 0.04
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 0.00012)