T39I (p.Thr39Ile) variant of FOXO1 (Forkhead box protein O1)
T39I (p.Thr39Ile) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data.
T39I (p.Thr39Ile) variant details
- p.Thr39Ile
- TOPMed rs1221703625
- gnomAD rs1221703625
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.36
- MetaLR 0.80
- MetaSVM 0.63
- CADD 26.20
- PolyPhen-2 0.86
- SIFT 0.03
- Most common in the East Asian population (allele frequency 3.7e-05)