S89C (p.Ser89Cys) variant of FOXO1 (Forkhead box protein O1)
S89C (p.Ser89Cys) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
S89C (p.Ser89Cys) variant details
- p.Ser89Cys
- gnomAD rs1290983226
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.26
- MetaLR 0.55
- MetaSVM -0.40
- CADD 17.50
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 0.00013)