S80R (p.Ser80Arg) variant of FOXO1 (Forkhead box protein O1)
S80R (p.Ser80Arg) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data.
S80R (p.Ser80Arg) variant details
- p.Ser80Arg
- TOPMed rs1183757708
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.28
- MetaLR 0.76
- MetaSVM 0.02
- CADD 22.70
- PolyPhen-2 0.53
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 0.00066)