S62L (p.Ser62Leu) variant of FOXO1 (Forkhead box protein O1)
S62L (p.Ser62Leu) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
S62L (p.Ser62Leu) variant details
- p.Ser62Leu
- gnomAD rs1878234649
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.24
- MetaLR 0.66
- MetaSVM -0.33
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the South Asian population (allele frequency 0.00021)