S47N (p.Ser47Asn) variant of FOXO1 (Forkhead box protein O1)
S47N (p.Ser47Asn) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data.
S47N (p.Ser47Asn) variant details
- p.Ser47Asn
- TOPMed rs1207899003
- gnomAD rs1207899003
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.22
- MetaLR 0.54
- MetaSVM -0.51
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the Latino/Admixed American population (allele frequency 0.0001)