S45* (p.Ser45Ter) variant of FOXO1 (Forkhead box protein O1)
S45* (p.Ser45Ter) in FOXO1 (Forkhead box protein O1) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data.
S45* (p.Ser45Ter) variant details
- p.Ser45Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.768
- CADD 37.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available