S41I (p.Ser41Ile) variant of FOXO1 (Forkhead box protein O1)
S41I (p.Ser41Ile) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
S41I (p.Ser41Ile) variant details
- p.Ser41Ile
- gnomAD rs1279773350
- Missense
- Variant Prioritization Score for Impact Estimate 0.541
- REVEL 0.38
- MetaLR 0.87
- MetaSVM 0.99
- CADD 26.50
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the South Asian population (allele frequency 5e-05)