P5L (p.Pro5Leu) variant of FOXO1 (Forkhead box protein O1)
P5L (p.Pro5Leu) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
P5L (p.Pro5Leu) variant details
- p.Pro5Leu
- TOPMed rs1036211926
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.34
- MetaLR 0.69
- MetaSVM 0.17
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 7.6e-05)