P52T (p.Pro52Thr) variant of FOXO1 (Forkhead box protein O1)
P52T (p.Pro52Thr) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data.
P52T (p.Pro52Thr) variant details
- p.Pro52Thr
- TOPMed rs970585546
- gnomAD rs970585546
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.14
- MetaLR 0.68
- MetaSVM -0.02
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 0.00048)