P42A (p.Pro42Ala) variant of FOXO1 (Forkhead box protein O1)
P42A (p.Pro42Ala) in FOXO1 (Forkhead box protein O1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data.
P42A (p.Pro42Ala) variant details
- p.Pro42Ala
- TOPMed rs931846569
- gnomAD rs931846569
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- REVEL 0.42
- MetaLR 0.81
- MetaSVM 0.52
- CADD 24.00
- PolyPhen-2 0.99
- SIFT 0.05
- Most common in the East Asian population (allele frequency 3.7e-05)